Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors

BACKGROUND: Directly targeting therapeutic suicide gene to a solid tumor is a hopeful approach for cancer gene therapy. Treatment of a solid tumor by an effective vector for a suicide gene remains a challenge. Given the lack of effective treatments, we constructed a bifidobacterial recombinant thymi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Changdong, Ma, Yongping, Hu, Qiongwen, Xie, Tingting, Wu, Jiayan, Zeng, Fan, Song, Fangzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964087/
https://www.ncbi.nlm.nih.gov/pubmed/27464624
http://dx.doi.org/10.1186/s12885-016-2608-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964087/
https://www.ncbi.nlm.nih.gov/pubmed/27464624
http://dx.doi.org/10.1186/s12885-016-2608-3

Ejemplares similares