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Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells
BACKGROUND: HER2/neu-positive breast cancer cells have recently been shown to use a unique Warburg-like metabolism for survival and aggressive behavior. These cells exhibit increased fatty acid synthesis and storage compared to normal breast cells or other tumor cells. Disruption of this synthetic p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964104/ https://www.ncbi.nlm.nih.gov/pubmed/27464732 http://dx.doi.org/10.1186/s12885-016-2611-8 |