Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells

BACKGROUND: HER2/neu-positive breast cancer cells have recently been shown to use a unique Warburg-like metabolism for survival and aggressive behavior. These cells exhibit increased fatty acid synthesis and storage compared to normal breast cells or other tumor cells. Disruption of this synthetic p...

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Detalles Bibliográficos
Autores principales: Baumann, Jan, Wong, Jason, Sun, Yan, Conklin, Douglas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964104/
https://www.ncbi.nlm.nih.gov/pubmed/27464732
http://dx.doi.org/10.1186/s12885-016-2611-8

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