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Inhibition of Regulatory Volume Decrease Enhances the Cytocidal Effect of Hypotonic Shock in Hepatocellular Carcinoma

Background: Hypotonic shock induces cytocidal effects through cell rupture, and cancer therapy based on this mechanism has been clinically administered to hepatocellular carcinoma patients. We herein investigated the effectiveness of hypotonic shock combined with the inhibition of regulatory volume...

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Detalles Bibliográficos
Autores principales: Kudou, Michihiro, Shiozaki, Atsushi, Kosuga, Toshiyuki, Ichikawa, Daisuke, Konishi, Hirotaka, Morimura, Ryo, Komatsu, Shuhei, Ikoma, Hisashi, Fujiwara, Hitoshi, Okamoto, Kazuma, Hosogi, Shigekuni, Nakahari, Takashi, Marunaka, Yoshinori, Otsuji, Eigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964136/
https://www.ncbi.nlm.nih.gov/pubmed/27471568
http://dx.doi.org/10.7150/jca.15181