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Inhibition of Regulatory Volume Decrease Enhances the Cytocidal Effect of Hypotonic Shock in Hepatocellular Carcinoma
Background: Hypotonic shock induces cytocidal effects through cell rupture, and cancer therapy based on this mechanism has been clinically administered to hepatocellular carcinoma patients. We herein investigated the effectiveness of hypotonic shock combined with the inhibition of regulatory volume...
Autores principales: | Kudou, Michihiro, Shiozaki, Atsushi, Kosuga, Toshiyuki, Ichikawa, Daisuke, Konishi, Hirotaka, Morimura, Ryo, Komatsu, Shuhei, Ikoma, Hisashi, Fujiwara, Hitoshi, Okamoto, Kazuma, Hosogi, Shigekuni, Nakahari, Takashi, Marunaka, Yoshinori, Otsuji, Eigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964136/ https://www.ncbi.nlm.nih.gov/pubmed/27471568 http://dx.doi.org/10.7150/jca.15181 |
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