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Bleomycin (BLM) Induces Epithelial-to-Mesenchymal Transition in Cultured A549 Cells via the TGF-β/Smad Signaling Pathway

The epithelial-to-mesenchymal transition (EMT) is a crucial cellular event in wound healing, tissue repair, and cancer progression in adult tissues, with the interactions with numerous signals. In this study, we aimed to determine whether bleomycin (BLM), an agent that causes pulmonary fibrosis, ind...

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Detalles Bibliográficos
Autores principales: Chen, Kui-Jun, Li, Qing, Wen, Cang-mei, Duan, Zhao-Xia, Zhang, Jie yuan, Xu, Chuan, Wang, Jian-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964140/
https://www.ncbi.nlm.nih.gov/pubmed/27471572
http://dx.doi.org/10.7150/jca.15566