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Invasiveness of pharmacokinetic studies in children: a systematic review

OBJECTIVES: To explore whether pharmacokinetic (PK) studies in paediatric patients are becoming less invasive. This will be evaluated by analysing the number of samples and volume of blood collected for each study within four different decades. METHODS: A systematic literature review was performed t...

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Detalles Bibliográficos
Autores principales: Altamimi, Mohammed I, Choonara, Imti, Sammons, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964204/
https://www.ncbi.nlm.nih.gov/pubmed/27431899
http://dx.doi.org/10.1136/bmjopen-2015-010484