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Invasiveness of pharmacokinetic studies in children: a systematic review
OBJECTIVES: To explore whether pharmacokinetic (PK) studies in paediatric patients are becoming less invasive. This will be evaluated by analysing the number of samples and volume of blood collected for each study within four different decades. METHODS: A systematic literature review was performed t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964204/ https://www.ncbi.nlm.nih.gov/pubmed/27431899 http://dx.doi.org/10.1136/bmjopen-2015-010484 |