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Melanoma dormancy in a mouse model is linked to GILZ/FOXO3A-dependent quiescence of disseminated stem-like cells

Metastatic cancer relapses following the reactivation of dormant, disseminated tumour cells; however, the cells and factors involved in this reactivation are just beginning to be identified. Using an immunotherapy-based syngeneic model of melanoma dormancy and GFP-labelled dormant cell-derived cell...

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Detalles Bibliográficos
Autores principales: Touil, Yasmine, Segard, Pascaline, Ostyn, Pauline, Begard, Severine, Aspord, Caroline, El Machhour, Raja, Masselot, Bernadette, Vandomme, Jerome, Flamenco, Pilar, Idziorek, Thierry, Figeac, Martin, Formstecher, Pierre, Quesnel, Bruno, Polakowska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964333/
https://www.ncbi.nlm.nih.gov/pubmed/27465291
http://dx.doi.org/10.1038/srep30405