C-terminal domain of p42 Ebp1 is essential for down regulation of p85 subunit of PI3K, inhibiting tumor growth

Potential tumor suppressor p42, ErbB3-binding protein 1 (EBP1) inhibits phosphoinositide 3-kinase (PI3K) activity reducing the p85 regulatory subunit. In this study, we demonstrated that overexpression of p42 promoted not only a reduction of wild type of p85 subunit but also oncogenic mutant forms o...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Inwoo, Kim, Chung Kwon, Ko, Hyo Rim, Park, Kye Won, Cho, Sung-Woo, Ahn, Jee-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964336/
https://www.ncbi.nlm.nih.gov/pubmed/27464702
http://dx.doi.org/10.1038/srep30626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964336/
https://www.ncbi.nlm.nih.gov/pubmed/27464702
http://dx.doi.org/10.1038/srep30626

Ejemplares similares