Dexmedetomidine Protects Rat Liver against Ischemia-Reperfusion Injury Partly by the α(2A)-Adrenoceptor Subtype and the Mechanism Is Associated with the TLR4/NF-κB Pathway

Toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) signaling plays a dominant role in the pathogenesis of liver ischemia-reperfusion (IR) injury. Dexmedetomidine (Dex) protects the liver against IR injury via α(2)-adrenoceptor activation, but the contribution of TLR4 signaling remains unknow...

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Detalles Bibliográficos
Autores principales: Wang, Yiheng, Wu, Shan, Yu, Xiaofang, Zhou, Shaoli, Ge, Mian, Chi, Xinjin, Cai, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964371/
https://www.ncbi.nlm.nih.gov/pubmed/27347929
http://dx.doi.org/10.3390/ijms17070995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964371/
https://www.ncbi.nlm.nih.gov/pubmed/27347929
http://dx.doi.org/10.3390/ijms17070995

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