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Brusatol Enhances the Radiosensitivity of A549 Cells by Promoting ROS Production and Enhancing DNA Damage

NF-E2-related factor 2 (Nrf2) has been identified as a master regulatory factor in the protection of cells from oxidative and electrophilic stress. However, overexpression of Nrf2 in lung cancer may cause chemoresistance, as well as radioresistance. In this study, we examined the relationship betwee...

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Detalles Bibliográficos
Autores principales: Sun, Xiaohui, Wang, Qin, Wang, Yan, Du, Liqing, Xu, Chang, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964373/
https://www.ncbi.nlm.nih.gov/pubmed/27347930
http://dx.doi.org/10.3390/ijms17070997