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Site-Specific Genome Engineering in Human Pluripotent Stem Cells

The possibility to generate patient-specific induced pluripotent stem cells (iPSCs) offers an unprecedented potential of applications in clinical therapy and medical research. Human iPSCs and their differentiated derivatives are tools for diseases modelling, drug discovery, safety pharmacology, and...

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Detalles Bibliográficos
Autores principales: Merkert, Sylvia, Martin, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964376/
https://www.ncbi.nlm.nih.gov/pubmed/27347935
http://dx.doi.org/10.3390/ijms17071000