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The Role of Genetic Polymorphisms as Related to One-Carbon Metabolism, Vitamin B6, and Gene–Nutrient Interactions in Maintaining Genomic Stability and Cell Viability in Chinese Breast Cancer Patients

Folate-mediated one-carbon metabolism (FMOCM) is linked to DNA synthesis, methylation, and cell proliferation. Vitamin B6 (B6) is a cofactor, and genetic polymorphisms of related key enzymes, such as serine hydroxymethyltransferase (SHMT), methionine synthase reductase (MTRR), and methionine synthas...

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Detalles Bibliográficos
Autores principales: Wu, Xiayu, Xu, Weijiang, Zhou, Tao, Cao, Neng, Ni, Juan, Zou, Tianning, Liang, Ziqing, Wang, Xu, Fenech, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964379/
https://www.ncbi.nlm.nih.gov/pubmed/27347936
http://dx.doi.org/10.3390/ijms17071003