Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position

The first Pt(IV) derivative of oxaliplatin carrying a ligand for TSPO (the 18-kDa mitochondrial translocator protein) has been developed. The expression of the translocator protein in the brain and liver of healthy humans is usually low, oppositely to steroid-synthesizing and rapidly proliferating t...

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Detalles Bibliográficos
Autores principales: Savino, Salvatore, Denora, Nunzio, Iacobazzi, Rosa Maria, Porcelli, Letizia, Azzariti, Amalia, Natile, Giovanni, Margiotta, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964386/
https://www.ncbi.nlm.nih.gov/pubmed/27347942
http://dx.doi.org/10.3390/ijms17071010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964386/
https://www.ncbi.nlm.nih.gov/pubmed/27347942
http://dx.doi.org/10.3390/ijms17071010

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