Hypoxia Potentiates Anabolic Effects of Exogenous Hyaluronic Acid in Rat Articular Cartilage

Hyaluronic acid (HA) is used clinically to treat osteoarthritis (OA), but its pharmacological effects under hypoxic conditions remain unclear. Articular chondrocytes in patients with OA are exposed to a hypoxic environment. This study investigated whether hypoxia could potentiate the anabolic effect...

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Detalles Bibliográficos
Autores principales: Ichimaru, Shohei, Nakagawa, Shuji, Arai, Yuji, Kishida, Tsunao, Shin-Ya, Masaharu, Honjo, Kuniaki, Tsuchida, Shinji, Inoue, Hiroaki, Fujiwara, Hiroyoshi, Shimomura, Seiji, Mazda, Osam, Kubo, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964389/
https://www.ncbi.nlm.nih.gov/pubmed/27347945
http://dx.doi.org/10.3390/ijms17071013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964389/
https://www.ncbi.nlm.nih.gov/pubmed/27347945
http://dx.doi.org/10.3390/ijms17071013

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