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Mechanisms Underlying Activation of α(1)-Adrenergic Receptor-Induced Trafficking of AQP5 in Rat Parotid Acinar Cells under Isotonic or Hypotonic Conditions

Defective cellular trafficking of aquaporin-5 (AQP5) to the apical plasma membrane (APM) in salivary glands is associated with the loss of salivary fluid secretion. To examine mechanisms of α(1)-adrenoceptor (AR)-induced trafficking of AQP5, immunoconfocal microscopy and Western blot analysis were u...

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Detalles Bibliográficos
Autores principales: Bragiel, Aneta M., Wang, Di, Pieczonka, Tomasz D., Shono, Masayuki, Ishikawa, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964398/
https://www.ncbi.nlm.nih.gov/pubmed/27367668
http://dx.doi.org/10.3390/ijms17071022