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TSPO PIGA Ligands Promote Neurosteroidogenesis and Human Astrocyte Well-Being

The steroidogenic 18 kDa translocator protein (TSPO) is an emerging, attractive therapeutic tool for several pathological conditions of the nervous system. Here, 13 high affinity TSPO ligands belonging to our previously described N,N-dialkyl-2-phenylindol-3-ylglyoxylamide (PIGA) class were evaluated...

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Detalles Bibliográficos
Autores principales: Da Pozzo, Eleonora, Giacomelli, Chiara, Costa, Barbara, Cavallini, Chiara, Taliani, Sabrina, Barresi, Elisabetta, Da Settimo, Federico, Martini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964404/
https://www.ncbi.nlm.nih.gov/pubmed/27367681
http://dx.doi.org/10.3390/ijms17071028