Neuroprotective Effect of Puerarin on Glutamate-Induced Cytotoxicity in Differentiated Y-79 Cells via Inhibition of ROS Generation and Ca(2+) Influx

Glutamate toxicity is estimated to be the key cause of photoreceptor degeneration in the pathogenesis of retinal degenerative diseases. Oxidative stress and Ca(2+) influx induced by glutamate are responsible for the apoptosis process of photoreceptor degeneration. Puerarin, a primary component of Ku...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Zhu, Xue, Zhang, Kai, Wu, Zhifeng, Sun, Song, Zhou, Fanfan, Zhu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964484/
https://www.ncbi.nlm.nih.gov/pubmed/27409614
http://dx.doi.org/10.3390/ijms17071109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964484/
https://www.ncbi.nlm.nih.gov/pubmed/27409614
http://dx.doi.org/10.3390/ijms17071109

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