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Human Aquaporin-4 and Molecular Modeling: Historical Perspective and View to the Future

Among the different aquaporins (AQPs), human aquaporin-4 (hAQP4) has attracted the greatest interest in recent years as a new promising therapeutic target. Such a membrane protein is, in fact, involved in a multiple sclerosis-like immunopathology called Neuromyelitis Optica (NMO) and in several diso...

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Detalles Bibliográficos
Autores principales: Mangiatordi, Giuseppe Felice, Alberga, Domenico, Trisciuzzi, Daniela, Lattanzi, Gianluca, Nicolotti, Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964494/
https://www.ncbi.nlm.nih.gov/pubmed/27420052
http://dx.doi.org/10.3390/ijms17071119