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Niemann-Pick Type C2 Protein Mediates Hepatic Stellate Cells Activation by Regulating Free Cholesterol Accumulation

In chronic liver diseases, regardless of their etiology, the development of fibrosis is the first step toward the progression to cirrhosis, portal hypertension, and hepatocellular carcinoma. Hepatic stellate cells (HSCs) are the main profibrogenic cells that promote the pathogenesis of liver fibrosi...

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Detalles Bibliográficos
Autores principales: Twu, Yuh-Ching, Lee, Tzong-Shyuan, Lin, Yun-Lian, Hsu, Shih-Ming, Wang, Yuan-Hsi, Liao, Chia-Yu, Wang, Chung-Kwe, Liang, Yu-Chih, Liao, Yi-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964497/
https://www.ncbi.nlm.nih.gov/pubmed/27420058
http://dx.doi.org/10.3390/ijms17071122