Ligand and Structure-Based Approaches for the Identification of Peptide Deformylase Inhibitors as Antibacterial Drugs

Peptide deformylase (PDF) is a metalloprotease catalyzing the removal of a formyl group from newly synthesized proteins, which makes it an important antibacterial drug target. Given the importance of PDF inhibitors like actinonin in antibacterial drug discovery, several reported potent PDF inhibitor...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Liang, Li, Zhu, Yasheng, Qiu, Shengzhi, Wang, Tao, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964514/
https://www.ncbi.nlm.nih.gov/pubmed/27428963
http://dx.doi.org/10.3390/ijms17071141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964514/
https://www.ncbi.nlm.nih.gov/pubmed/27428963
http://dx.doi.org/10.3390/ijms17071141

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