Revisiting the Lamotrigine-Mediated Effect on Hippocampal GABAergic Transmission

Lamotrigine (LTG) is generally considered as a voltage-gated sodium (Na(v)) channel blocker. However, recent studies suggest that LTG can also serve as a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel enhancer and can increase the excitability of GABAergic interneurons (INs). Peri...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Yu-Yin, Liu, Yu-Chao, Lee, Cheng-Ta, Lin, Yen-Chu, Wang, Mong-Lien, Yang, Yi-Ping, Chang, Kaung-Yi, Chiou, Shih-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964560/
https://www.ncbi.nlm.nih.gov/pubmed/27455251
http://dx.doi.org/10.3390/ijms17071191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964560/
https://www.ncbi.nlm.nih.gov/pubmed/27455251
http://dx.doi.org/10.3390/ijms17071191

Ejemplares similares