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Revisiting the Lamotrigine-Mediated Effect on Hippocampal GABAergic Transmission
Lamotrigine (LTG) is generally considered as a voltage-gated sodium (Na(v)) channel blocker. However, recent studies suggest that LTG can also serve as a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel enhancer and can increase the excitability of GABAergic interneurons (INs). Peri...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964560/ https://www.ncbi.nlm.nih.gov/pubmed/27455251 http://dx.doi.org/10.3390/ijms17071191 |