Cargando…
Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obesity-related genes and metabolic parameters
Extracellular matrix (ECM) remodeling dynamically occurs to accommodate adipose tissue expansion during obesity. One non-fibrillar component of ECM, biglycan, is released from the matrix in response to tissue stress; the soluble form of biglycan binds to toll-like receptor 2/4 on macrophages, causin...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964581/ https://www.ncbi.nlm.nih.gov/pubmed/27465988 http://dx.doi.org/10.1038/srep30609 |