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Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obesity-related genes and metabolic parameters

Extracellular matrix (ECM) remodeling dynamically occurs to accommodate adipose tissue expansion during obesity. One non-fibrillar component of ECM, biglycan, is released from the matrix in response to tissue stress; the soluble form of biglycan binds to toll-like receptor 2/4 on macrophages, causin...

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Detalles Bibliográficos
Autores principales:	Kim, Jimin, Lee, Seul Ki, Shin, Ji-min, Jeoun, Un-woo, Jang, Yeon Jin, Park, Hye Soon, Kim, Jong-Hyeok, Gong, Gyung-Yub, Lee, Taik Jong, Hong, Joon Pio, Lee, Yeon Ji, Heo, Yoon-Suk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964581/ https://www.ncbi.nlm.nih.gov/pubmed/27465988 http://dx.doi.org/10.1038/srep30609

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