Engineering Salmonella as intracellular factory for effective killing of tumour cells

Salmonella have many desirable properties as antitumour-agent due to its ability to proliferate inside tumours and induce tumour regression. Additionally, this bacterium can be genetically engineered to deliver therapeutic proteins intratumourally. The main limitation of this approach is the efficie...

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Detalles Bibliográficos
Autores principales: Camacho, Eva María, Mesa-Pereira, Beatriz, Medina, Carlos, Flores, Amando, Santero, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964584/
https://www.ncbi.nlm.nih.gov/pubmed/27464652
http://dx.doi.org/10.1038/srep30591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964584/
https://www.ncbi.nlm.nih.gov/pubmed/27464652
http://dx.doi.org/10.1038/srep30591

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