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Altered protein phosphorylation as a resource for potential AD biomarkers

The amyloidogenic peptide, Aβ, provokes a series of events affecting distinct cellular pathways regulated by protein phosphorylation. Aβ inhibits protein phosphatases in a dose-dependent manner, thus it is expected that the phosphorylation state of specific proteins would be altered in response to A...

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Detalles Bibliográficos
Autores principales: Henriques, Ana Gabriela, Müller, Thorsten, Oliveira, Joana Machado, Cova, Marta, da Cruz e Silva, Cristóvão B., da Cruz e Silva, Odete A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964585/
https://www.ncbi.nlm.nih.gov/pubmed/27466139
http://dx.doi.org/10.1038/srep30319