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Exome-based Variant Detection in Core Promoters

Core promoter controls the initiation of transcription. Core promoter sequence change can disrupt transcriptional regulation, lead to impairment of gene expression and ultimately diseases. Therefore, comprehensive characterization of core promoters is essential to understand normal and abnormal gene...

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Detalles Bibliográficos
Autores principales: Kim, Yeong C., Cui, Jian, Luo, Jiangtao, Xiao, Fengxia, Downs, Bradley, Wang, San Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964598/
https://www.ncbi.nlm.nih.gov/pubmed/27464681
http://dx.doi.org/10.1038/srep30716