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Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk

To identify susceptibility genes for osteoporosis, we conducted an integrative analysis that combined epigenomic elements and previous genome-wide association studies (GWASs) data, followed by validation at population and functional levels, which could identify common regulatory elements and predict...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Dong, Shan-Shan, Chen, Xiao-Feng, Jing, Ying-Aisha, Yang, Man, Yan, Han, Shen, Hui, Chen, Xiang-Ding, Tan, Li-Jun, Tian, Qing, Deng, Hong-Wen, Yang, Tie-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964617/
https://www.ncbi.nlm.nih.gov/pubmed/27465306
http://dx.doi.org/10.1038/srep30558