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Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic

Ebola virus (EBOV) is highly pathogenic, with a predisposition to cause outbreaks in human populations accompanied by significant mortality. An ovine polyclonal antibody therapy has been developed against EBOV, named EBOTAb. When tested in the stringent guinea pig model of EBOV disease, EBOTAb has b...

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Detalles Bibliográficos
Autores principales: Dowall, Stuart D., Bosworth, Andrew, Rayner, Emma, Taylor, Irene, Landon, John, Cameron, Ian, Coxon, Ruth, Al Abdulla, Ibrahim, Graham, Victoria A., Hall, Graham, Kobinger, Gary, Hewson, Roger, Carroll, Miles W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964638/
https://www.ncbi.nlm.nih.gov/pubmed/27465308
http://dx.doi.org/10.1038/srep30497