Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually worldwide(1). No approved antivirals are available to date and clinical trials with a tetravalen...

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Detalles Bibliográficos
Autores principales: Marceau, Caleb D., Puschnik, Andreas S., Majzoub, Karim, Ooi, Yaw Shin, Brewer, Susan M., Fuchs, Gabriele, Swaminathan, Kavya, Mata, Miguel A., Elias, Joshua E., Sarnow, Peter, Carette, Jan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964798/
https://www.ncbi.nlm.nih.gov/pubmed/27383987
http://dx.doi.org/10.1038/nature18631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964798/
https://www.ncbi.nlm.nih.gov/pubmed/27383987
http://dx.doi.org/10.1038/nature18631

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