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Neuroprotective properties of the PrP-like Shadoo glycoprotein assessed in the middle cerebral artery occlusion model of ischemia
Biochemical similarities have been noted between the natively unstructured region of the cellular prion protein, PrP(C), and a GPI-linked glycoprotein called Shadoo (Sho); these proteins are encoded by the Prnp and Sprn genes, respectively. Both proteins are expressed in the adult central nervous sy...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964864/ https://www.ncbi.nlm.nih.gov/pubmed/26516793 http://dx.doi.org/10.1080/19336896.2015.1105432 |