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Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions
Disease-related prion protein (PrP(Sc)), which is a structural isoform of the host-encoded cellular prion protein, is thought to be a causative agent of transmissible spongiform encephalopathies. However, the specific role of PrP(Sc) in prion pathogenesis and its relationship to infectivity remain c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964868/ https://www.ncbi.nlm.nih.gov/pubmed/26555211 http://dx.doi.org/10.1080/19336896.2015.1111507 |