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An analysis of the impact of pre‐analytical factors on the urine proteome: Sample processing time, temperature, and proteolysis

PURPOSE: We have examined the impact of sample processing time delay, temperature, and the addition of protease inhibitors (PIs) on the urinary proteome and peptidome, an important aspect of biomarker studies. EXPERIMENTAL DESIGN: Ten urine samples from patients with varying pathologies were each di...

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Detalles Bibliográficos
Autores principales: Hepburn, Sophie, Cairns, David A., Jackson, David, Craven, Rachel A., Riley, Beverley, Hutchinson, Michelle, Wood, Steven, Smith, Matthew Welberry, Thompson, Douglas, Banks, Rosamonde E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964914/
https://www.ncbi.nlm.nih.gov/pubmed/25400092
http://dx.doi.org/10.1002/prca.201400079