Genotype-Phenotype Associations of the CD-Associated Single Nucleotide Polymorphism within the Gene Locus Encoding Protein Tyrosine Phosphatase Non-Receptor Type 22 in Patients of the Swiss IBD Cohort

BACKGROUND: Protein tyrosine phosphatase non-receptor type 22 (PTPN22) plays an important role in immune cell function and intestinal homeostasis. The single nucleotide polymorphism (SNP) rs2476601 within the PTPN22 gene locus results in aberrant function of PTPN22 protein and protects from Crohn’s...

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Detalles Bibliográficos
Autores principales: Spalinger, Marianne R., Zeitz, Jonas, Biedermann, Luc, Rossel, Jean-Benoit, Sulz, Michael C., Frei, Pascal, Scharl, Sylvie, Vavricka, Stephan R., Fried, Michael, Rogler, Gerhard, Scharl, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964985/
https://www.ncbi.nlm.nih.gov/pubmed/27467733
http://dx.doi.org/10.1371/journal.pone.0160215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964985/
https://www.ncbi.nlm.nih.gov/pubmed/27467733
http://dx.doi.org/10.1371/journal.pone.0160215

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