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pH-Responsive Polyethylene Glycol Monomethyl Ether-ε-Polylysine-G-Poly (Lactic Acid)-Based Nanoparticles as Protein Delivery Systems

The application of poly(lactic acid) for sustained protein delivery is restricted by the harsh pH inside carriers. In this study, we synthesized a pH-responsive comb-shaped block copolymer, polyethylene glycol monomethyl ether-ε-polylysine-g-poly (lactic acid) (PEP)to deliver protein (bovine serum a...

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Detalles Bibliográficos
Autores principales: Liu, Huiqin, Li, Yijia, Yang, Rui, Gao, Xiujun, Ying, Guoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964987/
https://www.ncbi.nlm.nih.gov/pubmed/27467072
http://dx.doi.org/10.1371/journal.pone.0159296