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Functional analysis of RYR1 variants linked to malignant hyperthermia

Malignant hyperthermia manifests as a rapid and sustained rise in temperature in response to pharmacological triggering agents, e.g. inhalational anesthetics and the muscle relaxant suxamethonium. Other clinical signs include an increase in end-tidal CO(2), increased O(2) consumption, as well as tac...

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Detalles Bibliográficos
Autores principales: Stephens, Jeremy, Schiemann, Anja H., Roesl, Cornelia, Miller, Dorota, Massey, Sean, Pollock, Neil, Bulger, Terasa, Stowell, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964997/
https://www.ncbi.nlm.nih.gov/pubmed/27857962
http://dx.doi.org/10.1080/23328940.2016.1153360