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Functional analysis of RYR1 variants linked to malignant hyperthermia
Malignant hyperthermia manifests as a rapid and sustained rise in temperature in response to pharmacological triggering agents, e.g. inhalational anesthetics and the muscle relaxant suxamethonium. Other clinical signs include an increase in end-tidal CO(2), increased O(2) consumption, as well as tac...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964997/ https://www.ncbi.nlm.nih.gov/pubmed/27857962 http://dx.doi.org/10.1080/23328940.2016.1153360 |