B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy

BACKGROUND: B-cell depletion can improve a variety of chronic inflammatory diseases, but does not appear beneficial for patients with Crohn’s disease. OBJECTIVE: To elucidate the involvement of B cells in Crohn’s disease, we here performed an ‘in depth’ analysis of intestinal and blood B-cells in th...

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Detalles Bibliográficos
Autores principales: Timmermans, Wilhelmina M. C., van Laar, Jan A. M., van der Houwen, Tim B., Kamphuis, Lieke S. J., Bartol, Sophinus J. W., Lam, King H., Ouwendijk, Rob J., Sparrow, Miles P., Gibson, Peter R., van Hagen, P. Martin, van Zelm, Menno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965034/
https://www.ncbi.nlm.nih.gov/pubmed/27468085
http://dx.doi.org/10.1371/journal.pone.0160103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965034/
https://www.ncbi.nlm.nih.gov/pubmed/27468085
http://dx.doi.org/10.1371/journal.pone.0160103

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