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Immune-Modulation by Epidermal Growth Factor Receptor Inhibitors: Implication on Anti-Tumor Immunity in Lung Cancer

Skin toxicity is the most common toxicity caused by Epidermal Growth Factor Receptor (EGFR) inhibitors, and has been associated with clinical efficacy. As EGFR inhibitors enhance the expression of antigen presenting molecules in affected skin keratinocytes, they may concurrently facilitate neo-antig...

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Detalles Bibliográficos
Autores principales: Im, Jin S., Herrmann, Amanda C., Bernatchez, Chantale, Haymaker, Cara, Molldrem, Jeffrey J., Hong, Waun Ki, Perez-Soler, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965069/
https://www.ncbi.nlm.nih.gov/pubmed/27467256
http://dx.doi.org/10.1371/journal.pone.0160004