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Differential Frequency of CD8+ T Cell Subsets in Multiple Sclerosis Patients with Various Clinical Patterns

Recent evidence points to a pathogenic role for CD8(+) cytotoxic T (Tc) cells in Multiple sclerosis (MS). Based on cytokine profile, Tc cells can be divided into different subsets: IFN-γ (Tc1), IL-4 (Tc2), IL-10 (Tc10), IL-17 (Tc17), IL-21 (Tc21), IL-22 (Tc22) and TNF-α producing cells. In this stud...

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Detalles Bibliográficos
Autores principales: Salehi, Zahra, Doosti, Rozita, Beheshti, Masoumeh, Janzamin, Ehsan, Sahraian, Mohammad Ali, Izad, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965085/
https://www.ncbi.nlm.nih.gov/pubmed/27467597
http://dx.doi.org/10.1371/journal.pone.0159565