Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune inflammatory disease affecting the joints. Anti-citrullinated protein antibodies (ACPA) are frequently found in RA. Previous studies identified a citrullinated epitope in cartilage proteoglycan (PG) aggrecan that elicited pro-inflammatory cytoki...

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Detalles Bibliográficos
Autores principales: Markovics, Adrienn, Ocskó, Tímea, Katz, Robert S., Buzás, Edit I., Glant, Tibor T., Mikecz, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965111/
https://www.ncbi.nlm.nih.gov/pubmed/27466816
http://dx.doi.org/10.1371/journal.pone.0160284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965111/
https://www.ncbi.nlm.nih.gov/pubmed/27466816
http://dx.doi.org/10.1371/journal.pone.0160284

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