Cargando…

Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune inflammatory disease affecting the joints. Anti-citrullinated protein antibodies (ACPA) are frequently found in RA. Previous studies identified a citrullinated epitope in cartilage proteoglycan (PG) aggrecan that elicited pro-inflammatory cytoki...

Descripción completa

Detalles Bibliográficos
Autores principales:	Markovics, Adrienn, Ocskó, Tímea, Katz, Robert S., Buzás, Edit I., Glant, Tibor T., Mikecz, Katalin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965111/ https://www.ncbi.nlm.nih.gov/pubmed/27466816 http://dx.doi.org/10.1371/journal.pone.0160284

Ejemplares similares

Characterization and Localization of Citrullinated Proteoglycan Aggrecan in Human Articular Cartilage
por: Glant, Tibor T., et al.
Publicado: (2016)

Vaccination by Two DerG LEAPS Conjugates Incorporating Distinct Proteoglycan (PG, Aggrecan) Epitopes Provides Therapy by Different Immune Mechanisms in a Mouse Model of Rheumatoid Arthritis
por: Zimmerman, Daniel H., et al.
Publicado: (2021)

Proteoglycan Aggrecan Conducting T Cell Activation and Apoptosis in a Murine Model of Rheumatoid Arthritis
por: Hanyecz, A., et al.
Publicado: (2014)

Suppression of Proteoglycan-Induced Autoimmune Arthritis by Myeloid-Derived Suppressor Cells Generated In Vitro from Murine Bone Marrow
por: Kurkó, Júlia, et al.
Publicado: (2014)

Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints
por: Angyal, Adrienn, et al.
Publicado: (2010)

Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase
por: Markovics, Adrienn, et al.
Publicado: (2020)

Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis
por: Kaplan, Charles, et al.
Publicado: (2002)

Epigenetics in the pathogenesis of rheumatoid arthritis
por: Glant, Tibor T, et al.
Publicado: (2014)

Age-related changes in arthritis susceptibility and severity in a murine model of rheumatoid arthritis
por: Tarjanyi, Oktavia, et al.
Publicado: (2009)

BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance
por: Farkas, Balint, et al.
Publicado: (2009)

Enigma of IL-17 and Th17 Cells in Rheumatoid Arthritis and in Autoimmune Animal Models of Arthritis
por: Kugyelka, Reka, et al.
Publicado: (2016)

Non-MHC Risk Alleles in Rheumatoid Arthritis and in the Syntenic Chromosome Regions of Corresponding Animal Models
por: Besenyei, Timea, et al.
Publicado: (2012)

Identification of myeloid-derived suppressor cells in the synovial fluid of patients with rheumatoid arthritis: a pilot study
por: Kurkó, Júlia, et al.
Publicado: (2014)

Histidine deficiency does not protect against aggrecan-induced arthritis
por: Nagy, Gyorgy, et al.
Publicado: (2007)

IL-10 Is Critically Involved in Mycobacterial HSP70 Induced Suppression of Proteoglycan-Induced Arthritis
por: Wieten, Lotte, et al.
Publicado: (2009)

Regulatory role of capsaicin-sensitive peptidergic sensory nerves in the proteoglycan-induced autoimmune arthritis model of the mouse
por: Horváth, Ádám, et al.
Publicado: (2018)

Restoring the Balance between Pro-Inflammatory and Anti-Inflammatory Cytokines in the Treatment of Rheumatoid Arthritis: New Insights from Animal Models
por: Markovics, Adrienn, et al.
Publicado: (2021)

T(h)1/T(h)17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice
por: Boldizsar, Ferenc, et al.
Publicado: (2009)

Testing if Micro-CT Is Capable of Quantitating the Extent of Proteoglycan-Aggrecan Induced Axial Spondyloarthritis in Mice
por: Han, Qing, et al.
Publicado: (2021)

Attenuation of Collagen-Induced Arthritis in Mice by Salmon Proteoglycan
por: Yoshimura, Sayuri, et al.
Publicado: (2014)

Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice
por: Szántó, Sándor, et al.
Publicado: (2007)

Patients with rheumatoid arthritis have an altered circulatory aggrecan profile
por: Rousseau, Jean C, et al.
Publicado: (2008)

Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation
por: Adarichev, Vyacheslav A, et al.
Publicado: (2005)

Phenome‐Wide Association Study of Autoantibodies to Citrullinated and Noncitrullinated Epitopes in Rheumatoid Arthritis
por: Liao, Katherine P., et al.
Publicado: (2017)

Citrullination modulates antigen processing and presentation by revealing cryptic epitopes in rheumatoid arthritis
por: Curran, Ashley M., et al.
Publicado: (2023)

Salivary citrullinated proteins in rheumatoid arthritis and associated periodontal disease
por: Tar, Ildikó, et al.
Publicado: (2021)

Aggrecan Turnover in Women with Rheumatoid Arthritis Treated with TNF-α Inhibitors
por: Szeremeta, Anna, et al.
Publicado: (2020)

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans
por: Iozzo, Renato V., et al.
Publicado: (2015)

Rheumatoid arthritis and smoking: putting the pieces together
por: Baka, Zsuzsanna, et al.
Publicado: (2009)

Citrullination and Carbamylation in the Pathophysiology of Rheumatoid Arthritis
por: Pruijn, Ger J. M.
Publicado: (2015)

Antibodies to synthetic citrullinated peptide epitope correlate with disease activity and flares in rheumatoid arthritis
por: Khatri, Sangita, et al.
Publicado: (2020)

Clinical Implications of Shared Epitope and Anti-citrullinated Peptide Antibody in Patients With Rheumatoid Arthritis
por: Jung, Seung Min, et al.
Publicado: (2022)

Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies
por: Reed, Evan, et al.
Publicado: (2016)

Physical Characteristics of a Citrullinated Pro-Filaggrin Epitope Recognized by Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Sera
por: Trier, Nicole Hartwig, et al.
Publicado: (2016)

Glycosaminoglycans and Proteoglycans
por: Pomin, Vitor H., et al.
Publicado: (2018)

Articular cartilage and changes in arthritis: Noncollagenous proteins and proteoglycans in the extracellular matrix of cartilage
por: Roughley, Peter J
Publicado: (2001)

Aggrecan, the Primary Weight-Bearing Cartilage Proteoglycan, Has Context-Dependent, Cell-Directive Properties in Embryonic Development and Neurogenesis: Aggrecan Glycan Side Chain Modifications Convey Interactive Biodiversity
por: Hayes, Anthony J, et al.
Publicado: (2020)

Sphingosine-1-phosphate attenuates proteoglycan aggrecan expression via production of prostaglandin E(2 )from human articular chondrocytes
por: Masuko, Kayo, et al.
Publicado: (2007)

Shared recognition of citrullinated tenascin-C peptides by T and B cells in rheumatoid arthritis
por: Song, Jing, et al.
Publicado: (2021)

Mapping of citrullinated fibrinogen B-cell epitopes in rheumatoid arthritis by imaging surface plasmon resonance
por: van Beers, Joyce JBC, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_h57ppl283lus4nuhhi0d5u890i