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Endothelial-Specific EphA4 Negatively Regulates Native Pial Collateral Formation and Re-Perfusion following Hindlimb Ischemia

Leptomeningeal anastomoses play a critical role in regulating vascular re-perfusion following obstruction, however, the mechanisms regulating their development remains under investingation. Our current findings indicate that EphA4 receptor is a novel negative regulator of collaterogenesis. We demons...

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Detalles Bibliográficos
Autores principales: Okyere, Benjamin, Giridhar, Kaavya, Hazy, Amanda, Chen, Miao, Keimig, David, Bielitz, Robert C., Xie, Hehuang, He, Jia-Qiang, Huckle, William R., Theus, Michelle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965112/
https://www.ncbi.nlm.nih.gov/pubmed/27467069
http://dx.doi.org/10.1371/journal.pone.0159930