Comparative Methods to Improve the Detection of BRAF V600 Mutations in Highly Pigmented Melanoma Specimens

Genotyping BRAF in melanoma samples is often challenging. The presence of melanin greatly interferes with thermostable DNA polymerases and/or nucleic acids in traditional polymerase chain reaction (PCR)-based methods. In the present work, we evaluated three easy-to-use strategies to improve the dete...

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Detalles Bibliográficos
Autores principales: Frouin, Eric, Maudelonde, Thierry, Senal, Romain, Larrieux, Marion, Costes, Valérie, Godreuil, Sylvain, Vendrell, Julie A., Solassol, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965116/
https://www.ncbi.nlm.nih.gov/pubmed/27466810
http://dx.doi.org/10.1371/journal.pone.0158698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965116/
https://www.ncbi.nlm.nih.gov/pubmed/27466810
http://dx.doi.org/10.1371/journal.pone.0158698

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