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Ligand Similarity Complements Sequence, Physical Interaction, and Co-Expression for Gene Function Prediction

The expansion of protein-ligand annotation databases has enabled large-scale networking of proteins by ligand similarity. These ligand-based protein networks, which implicitly predict the ability of neighboring proteins to bind related ligands, may complement biologically-oriented gene networks, whi...

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Detalles Bibliográficos
Autores principales: O’Meara, Matthew J., Ballouz, Sara, Shoichet, Brian K., Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965129/
https://www.ncbi.nlm.nih.gov/pubmed/27467773
http://dx.doi.org/10.1371/journal.pone.0160098