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Influence of Repressive Histone and DNA Methylation upon D4Z4 Transcription in Non-Myogenic Cells

We looked at a disease-associated macrosatellite array D4Z4 and focused on epigenetic factors influencing its chromatin state outside of the disease-context. We used the HCT116 cell line that contains the non-canonical polyadenylation (poly-A) signal required to stabilize somatic transcripts of the...

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Detalles Bibliográficos
Autores principales: Das, Sunny, Chadwick, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965136/
https://www.ncbi.nlm.nih.gov/pubmed/27467759
http://dx.doi.org/10.1371/journal.pone.0160022