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Influence of Repressive Histone and DNA Methylation upon D4Z4 Transcription in Non-Myogenic Cells
We looked at a disease-associated macrosatellite array D4Z4 and focused on epigenetic factors influencing its chromatin state outside of the disease-context. We used the HCT116 cell line that contains the non-canonical polyadenylation (poly-A) signal required to stabilize somatic transcripts of the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965136/ https://www.ncbi.nlm.nih.gov/pubmed/27467759 http://dx.doi.org/10.1371/journal.pone.0160022 |