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The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection
The hydrolytic deamination of adenosine to inosine (A-to-I editing) in precursor mRNA induces variable gene products at the post-transcription level. How and to what extent A-to-I RNA editing diversifies transcriptome is not fully characterized in the evolution, and very little is known about the se...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965139/ https://www.ncbi.nlm.nih.gov/pubmed/27467689 http://dx.doi.org/10.1371/journal.pgen.1006191 |