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The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection

The hydrolytic deamination of adenosine to inosine (A-to-I editing) in precursor mRNA induces variable gene products at the post-transcription level. How and to what extent A-to-I RNA editing diversifies transcriptome is not fully characterized in the evolution, and very little is known about the se...

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Detalles Bibliográficos
Autores principales: Yu, Yao, Zhou, Hongxia, Kong, Yimeng, Pan, Bohu, Chen, Longxian, Wang, Hongbing, Hao, Pei, Li, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965139/
https://www.ncbi.nlm.nih.gov/pubmed/27467689
http://dx.doi.org/10.1371/journal.pgen.1006191