Cargando…

The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection

The hydrolytic deamination of adenosine to inosine (A-to-I editing) in precursor mRNA induces variable gene products at the post-transcription level. How and to what extent A-to-I RNA editing diversifies transcriptome is not fully characterized in the evolution, and very little is known about the se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Yao, Zhou, Hongxia, Kong, Yimeng, Pan, Bohu, Chen, Longxian, Wang, Hongbing, Hao, Pei, Li, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965139/ https://www.ncbi.nlm.nih.gov/pubmed/27467689 http://dx.doi.org/10.1371/journal.pgen.1006191

Ejemplares similares

RNA Editome in Rhesus Macaque Shaped by Purifying Selection
por: Chen, Jia-Yu, et al.
Publicado: (2014)

An Evolutionary Landscape of A-to-I RNA Editome across Metazoan Species
por: Hung, Li-Yuan, et al.
Publicado: (2017)

The landscape of the A-to-I RNA editome from 462 human genomes
por: Ouyang, Zhangyi, et al.
Publicado: (2018)

Editome landscape of CCM-derived endothelial cells
por: Scimone, Concetta, et al.
Publicado: (2022)

The evolutionary landscape of intergenic trans-splicing events in insects
por: Kong, Yimeng, et al.
Publicado: (2015)

Editome Disease Knowledgebase (EDK): a curated knowledgebase of editome-disease associations in human
por: Niu, Guangyi, et al.
Publicado: (2019)

Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples
por: Chigaev, Michael, et al.
Publicado: (2019)

Corrigendum: Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples
por: Chigaev, Michael, et al.
Publicado: (2020)

Spatial epitranscriptomics reveals A-to-I editome specific to cancer stem cell microniches
por: Lee, Amos C., et al.
Publicado: (2022)

Comprehensive Characterization of the RNA Editomes in Cancer Development and Progression
por: Luo, Haitao, et al.
Publicado: (2018)

Characterization of RNA editome in primary and metastatic lung adenocarcinomas
por: Peng, Lihua, et al.
Publicado: (2016)

Evaluation of the Interplay between the ADAR Editome and Immunotherapy in Melanoma
por: Tusup, Marina, et al.
Publicado: (2021)

Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior
por: Li, Qiye, et al.
Publicado: (2014)

Profiling the RNA editomes of wild-type C. elegans and ADAR mutants
por: Zhao, Han-Qing, et al.
Publicado: (2015)

Characterization of RNA Editome in the Mammary Gland of Yaks during the Lactation and Dry Periods
por: Wu, Xiaoyun, et al.
Publicado: (2022)

Landscape of tissue-specific RNA Editome provides insight into co-regulated and altered gene expression in pigs (Sus-scrofa)
por: Adetula, Adeyinka A., et al.
Publicado: (2021)

Developmental atlas of the RNA editome in Sus scrofa skeletal muscle
por: Yang, Yalan, et al.
Publicado: (2019)

The cellular and KSHV A-to-I RNA editome in primary effusion lymphoma and its role in the viral lifecycle
por: Rajendren, Suba, et al.
Publicado: (2023)

Adaptation of the Porcine Pituitary Transcriptome, Spliceosome and Editome during Early Pregnancy
por: Makowczenko, Karol G., et al.
Publicado: (2023)

Dynamic Editome of Zebrafish under Aminoglycosides Treatment and Its Potential Involvement in Ototoxicity
por: Yan, Sijia, et al.
Publicado: (2017)

The ADAR1 editome reveals drivers of editing-specificity for ADAR1-isoforms
por: Kleinova, Renata, et al.
Publicado: (2023)

Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis
por: Qiu, Si, et al.
Publicado: (2016)

Purifying and positive selection in the evolution of stop codons
por: Belinky, Frida, et al.
Publicado: (2018)

Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression
por: Han, Jian, et al.
Publicado: (2020)

Purifying selection shapes the coincident SNP distribution of primate coding sequences
por: Chen, Chia-Ying, et al.
Publicado: (2016)

Analysis of Genetic Variation Indicates DNA Shape Involvement in Purifying Selection
por: Wang, Xiaofei, et al.
Publicado: (2018)

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis
por: Deffit, Sarah N, et al.
Publicado: (2017)

Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development
por: Rajendren, Suba, et al.
Publicado: (2021)

Recent Activity in Expanding Populations and Purifying Selection Have Shaped Transposable Element Landscapes across Natural Accessions of the Mediterranean Grass Brachypodium distachyon
por: Stritt, Christoph, et al.
Publicado: (2017)

Population genetic and biophysical evidences reveal that purifying selection shapes the genetic landscape of Plasmodium falciparum RH ligands in Chhattisgarh and West Bengal, India
por: Ghoshal, Sharmistha, et al.
Publicado: (2020)

DeepEdit: single-molecule detection and phasing of A-to-I RNA editing events using nanopore direct RNA sequencing
por: Chen, Longxian, et al.
Publicado: (2023)

Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
por: Persi, Erez, et al.
Publicado: (2016)

Gene conversion and purifying selection shape nucleotide variation in gibbon L/M opsin genes
por: Hiwatashi, Tomohide, et al.
Publicado: (2011)

Selecting an Air Purifying System
Publicado: (2021)

Transcriptome, Spliceosome and Editome Expression Patterns of the Porcine Endometrium in Response to a Single Subclinical Dose of Salmonella Enteritidis Lipopolysaccharide
por: Paukszto, Lukasz, et al.
Publicado: (2020)

Positive and Purifying Selection Influence the Evolution of Doublesex in the Anastrepha fraterculus Species Group
por: Sobrinho, Iderval S., et al.
Publicado: (2012)

Discovery of positive and purifying selection in metagenomic time series of hypermutator microbial populations
por: Maddamsetti, Rohan, et al.
Publicado: (2022)

Decipher the ancestry of the plant-specific LBD gene family
por: Kong, Yimeng, et al.
Publicado: (2017)

Global RNA editome landscape discovers reduced RNA editing in glioma: loss of editing of gamma-amino butyric acid receptor alpha subunit 3 (GABRA3) favors glioma migration and invasion
por: Patil, Vikas, et al.
Publicado: (2020)

A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation
por: Wang, Fengjiao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ppm39l9fk8s88h4rsrq3loagdt