Up-Regulation of CYP2C19 Expression by BuChang NaoXinTong via PXR Activation in HepG2 Cells

BACKGROUND: Cytochrome P450 2C19 (CYP2C19) is an important drug-metabolizing enzyme (DME), which is responsible for the biotransformation of several kinds of drugs such as proton pump inhibitors, platelet aggregation inhibitors and antidepressants. Previous studies showed that Buchang NaoXinTong cap...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Lou, Xiao-Ya, Wu, Xiao-Ying, Wang, Huan, Qu, Qiang, Tan, Shen-Lan, Ruan, Jun-Shan, Qu, Jian, Chen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965156/
https://www.ncbi.nlm.nih.gov/pubmed/27467078
http://dx.doi.org/10.1371/journal.pone.0160285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965156/
https://www.ncbi.nlm.nih.gov/pubmed/27467078
http://dx.doi.org/10.1371/journal.pone.0160285

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